Changes in the Osmotic Activity of Liver and of Kidney Tissue Caused by Passage of Sodium Chloride, Urea, and Some Other Substances into Cells
نویسنده
چکیده
The osmotic activity of liver tissue and of kidney cortex tested within 10 minutes after immersion in solutions of sodium chloride has been increased by procedures which introduce sodium chloride, urea or creatinin into the body in excess of its elimination. A substance formed by cell metabolism, namely urea, can increase the osmotic activity of liver and of kidney cells. The amino acids, glycine and arginine, under similar conditions have not increased the osmotic activity of liver or of kidney cortex.
منابع مشابه
The Relation of Urea to the Movement of Water in Liver Tissue.
The purpose of this study has been to determine what conditions maintain the high level of osmotic pressure within liver cells present immediately after their removal from the body, to define the relation of water movement to this pressure, and to learn if intracellular osmotic pressure and water movement are changed when amino acids and related substances are transformed to produce urea. Signi...
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 103 شماره
صفحات -
تاریخ انتشار 1956